A low-cost strategy for 43Ca solid-state NMR spectroscopy

Solid-State NMR Spectroscopy

A number of arylamides have been synthesized and found to exhibit potent antimicrobial activities against a broad spectrum of Gram-positive and Gram-negative bacteria while exhibiting low toxicity toward eukaryotic cells. These facially amphiphilic foldamers have a relatively rigid intramolecular hydrogen-bonded arylamide as a framework, which places trifluormethyl versus positively charged ami...

Afterglow Solid-State NMR Spectroscopy.

Biomolecular solid-state NMR experiments have traditionally been collected through detection of 13C or 15N nuclei. Since these nuclei have relatively low sensitivity stemming from their smaller gyromagnetic ratios relative to 1H, the time required to collect multi-dimensional datasets serves as a limitation to resonance assignment and structure determination. One improvement in the field has be...

Solid - state NMR spectroscopy for structural investigations in materials science

A Low-Cost Solid State Clothesline Alarm

Modern electrical dryers are often equipped with end-ofcycle alarms, making their use more efficient and reducing the need for periodic monitoring. We believe that lowerincome households as well as ecologically aware consumers, drying their laundry on a clothesline, could benefit from a similar mechanism. Such an alarm must be simple to use, compatible with existing systems and low-cost. This w...

Fractional deuteration applied to biomolecular solid-state NMR spectroscopy

Solid-state Nuclear Magnetic Resonance can provide detailed insight into structural and dynamical aspects of complex biomolecules. With increasing molecular size, advanced approaches for spectral simplification and the detection of medium to long-range contacts become of critical relevance. We have analyzed the protonation pattern of a membrane-embedded ion channel that was obtained from bacter...